Table 3.
Effect of SAE, crocin and placebo on thyroid function in patients with schizophrenia, as mean ±SD
| Parameters Groups | Baseline | Week 2 | Week 6 | Week 12 | p | |
|---|---|---|---|---|---|---|
| TSH | SAE | 1.8±1.6 | 1.7±1.5 | 1.9±1.7 | 2.2±2.4 | 0.081 |
| Crocin | 1.3±0.8 | 1.7±1.2 | 1.7±1.2 | 1.6±1.0 | ||
| Placebo | 1.1±0.6 | 1.2±0.6 | 1.1±0.4 | 1.0±0.5 | ||
| T3 | SAE | 0.7±0.1 | 0.8±0.1 | 0.8±0.1 | 0.8±0.1 | 0.449 |
| Crocin | 0.7±0.1 | 0.8±0.1 | 0.8±0.1 | 0.8±0.1 | ||
| Placebo | 0.7±0.1 | 0.7±0.1 | 0.8±0.1 | 0.7±0.1 | ||
| SAE | 8.5±1. 8 | 8.5±1.8 | 8.6±1.7 | 8.5±1.8 | ||
| T4 | Crocin | 7.8±1.1 | 8.1±1.3 | 8.4±1.2 | 8.2±1.6 | 0.225 |
| Placebo | 7.8±1.4 | 7.5±1.4 | 8.1±1.3 | 7.8±1.6 | ||
TSH: Thyroid stimulating hormone; T3: triiodothyronine; T4: thyroxine