Figure 4. Alternative splicing of FOXP3 exon 7 correlates with IL-17A expression.

Quantitative PCR was used to measure FOXP3 and IL-17A transcript levels in colon biopsies from patients suffering from Crohn’s disease and normalized to GAPDH expression (n = 26). Data are presented as mean of n = 3 technical replicates. P < 0.05 was considered significant, Spearman rank correlation test; r = correlation coefficient).