Figure 1. Single-cell DamID mapping of genome–NL interactions.
(A) Schematic representation of the single-cell DamID procedure. HI, heat inactivation step. (B) NL contact maps for chr17 in six individual cells (black) and the average profile of 118 single cells (bottom track, green). OE, observed over expected read count ratio in contiguous 100 kb segments. (C) Grey scale representation of OE values for 118 single cells on chromosome 17. Grey bars underneath the axes in (B–C) mark unmappable regions; “c” is centromeric region. See also Figure S1.
