Skip to main content
. Author manuscript; available in PMC: 2016 May 18.
Published in final edited form as: Mol Psychiatry. 2015 Mar 17;21(1):108–117. doi: 10.1038/mp.2015.23

Table 1.

Association results (P<10−6) in novel AD loci among APOE ε4− subjects in the combined stage 1 and stage 2 samples.

SNP CH Region or Closest Gene MA MAF Stage 1
Stage 2
Stages 1 + 2
OR (95% CI) P OR (95% CI) P OR (95% CI) P
rs16847609 3 SOX14/CLDN18 A 0.09 1.21 (1.12–1.29) 2.3x10−7 1.09 (0.87–1.37) 0.47 1.19 (1.11–1.28) 5.3x10−7
rs382216 5 CDC42SE2-ACSL6 T 0.36 0.88 (0.83–0.93) 6.5x10−6 0.78 (0.67–0.91) 0.002 0.87 (0.82–0.92) 2.0x10−7
rs11168036 5 PFDN1/HBEGF T 0.50 1.14 (1.09–1.19) 9.3x10−9 0.97 (0.85–1.11) 0.64 1.12 (1.07–1.17) 3.2x10−7
rs2732703 17 KANSL1/LRRC37A G 0.13 0.73 (0.65–0.83) 6.4x10−7 0.71 (0.58–0.88) 0.001 0.73 (0.65–0.81) 5.8x10−9
rs71380849 17 CDR2L A 0.06 1.45 (1.24–1.70) 3.8x10−6 1.59 (1.01–2.50) 0.04 1.47 (1.26–1.71) 9.1x10−7