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. Author manuscript; available in PMC: 2016 Aug 4.
Published in final edited form as: Chem Commun (Camb). 2015 Aug 4;51(60):12134–12137. doi: 10.1039/c5cc04417k

Table 1.

Ranking of variables for transfection, uptake, and viability. The value of Acos(Θ) indicates the strength of the correlation.

Transfection Uptake Viability
Variable A(cosθ) Variable A(cosθ) Variable A(cosθ)
1 B 0.33 LogP* 0.27 HtF* 0.28
2 Uptake 0.23 B+S 0 27 B:S 0.13
3 LogP* 0.22 GFE* 0.27 HtF 0.08
4 B+S 0.21 MW* 0.27 GFE 0.07
5 GFE* 0.21 BP* 0.27 PDI −0.06
6 MW* 0.21 MP* 0.27 DP −0.07
7 BP* 0.21 CV* 0.27 tPSA −0.07
8 MP* 0.21 MR* 0.27 MP −0.08
9 CV* 0.21 B 0 26 BP −0.08
10 MR* 0.21 Transfection 0.23 Mw −0.08
11 Mn 0.20 LogP 0.18 MR −0.08
12 LogP 0.17 S 0.14 CV −0.08
13 CV 0.16 Mn 0.12 Mn −0.10
14 MR 0.16 CV 0.10 S −0.15
15 Mw 0.16 MR 0.10 LogP −0.18
16 BP 0.16 Mw 0.10 Transfection −0.22
17 MP 0.16 BP 0.10 Uptake −0.24
18 DP 0.16 MP 0.10 B −0.25
19 tPSA 0.16 tPSA 0.09 B+S −0.28
20 PDI 0.13 DP 0.09 GFE* −0.28
21 S 0.05 PDI 0.08 MW* −0.28
22 Viability −0.04 Viability −0.04 BP* −0.28
23 GFE −0.16 GFE −0.09 MP* −0.28
24 HtF −0.16 HtF −0.09 CV* −0.28
25 HtF* −0.21 B:S −0.15 MR* −0.28
26 B:S −0.25 HtF* −0.27 LogP* −0.28