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. Author manuscript; available in PMC: 2016 Nov 19.
Published in final edited form as: Neuroscience. 2015 Mar 12;309:84–99. doi: 10.1016/j.neuroscience.2015.03.007

Fig. 2.

Fig. 2

Therapeutic interventions. Pharmaceutical (e.g., IL-1RA, minocycline) interventions, exercise, and anti-oxidant rich diets have all been demonstrated to normalize the immunophenotype of the aged hippocampal microglia, thus reducing neuroinflammatory responses, and preventing long-term memory impairments.