TABLE 3.
Overall mean and median values for estrogen receptor, progesterone receptor, and Ki67 activity in lobule type 1, lobule type 2, and ducts, as well as the distribution of matched pair (for women using and not using HT) differences for each variable
| Overall | Differences matched | |||||
|---|---|---|---|---|---|---|
| Variable | Mean | Median (range) | 10% | Median | 90% | P |
| ER Lob1 | 5.4 | 0.1 (0-39.3) | −7.9 | 0.7 | 17.2 | 0.21 |
| ER Lob2 | 0.2 | 0.0 (0-3.6) | 0.0 | 0.0 | 2.9 | ND |
| ER ducts | 11.9 | 6.8 (0-55.4) | −30.3 | −2.6 | 10.1 | 0.18 |
| PR Lob1 | 6.4 | 0.6 (0-51.0) | −25.5 | 0.2 | 21.2 | 0.62 |
| PR Lob2 | 0.3 | 0.0 (0-9.3) | 0.0 | 0.0 | 0.0 | ND |
| PR duct | 13.7 | 11.4 (0-57.6) | −35.6 | −10.7 | 19.9 | 0.019 |
| Ki67 Lob1 | 0.5 | 0.0 (0-7.0) | −2.7 | 0.0 | 0.5 | 0.11 |
| Ki67 Lob2 | 0.0 | 0.0 (0-0.9) | 0.0 | 0.0 | 0.0 | ND |
| Ki67 ducts | 0.7 | 0.2 (0-6.1) | −3.1 | −0.6 | 0.1 | <0.001 |
ER, estrogen receptor; Lob1, lobule type 1; Lob2, lobule type 2; ND, not done; PR, progesterone receptor. P values in bold indicate statistical significance.