Table 2.
Overall summary of grade 3 or 4 adverse events
| Adverse event | Grade 3 | Grade 4 | Grades 1–5 |
|---|---|---|---|
| N (%) | N (%) | N (%) | |
| Back pain | 2 (14) | 0 | 7 (50) |
| Bone pain | 2 (14) | 0 | 6 (43) |
| Infusion reaction | 1 (7) | 0 | 2 (14) |
| Neutropenia | 2 (14) | 1 (7) | 8 (57) |
| Peripheral neuropathy | 2 (14) | 0 | 11 (79) |
| Hypertension | 1 (7) | 0 | 1 (7) |
| Myalgia | 1 (7) | 0 | 5 (36) |
| Headache | 1 (7) | 0 | 6 (43) |
| Dyspnea | 1 (7) | 0 | 5 (36) |
| Diarrhea | 2 (14) | 0 | 7 (50) |
| Dehydration | 1 (7) | 0 | 1 (7) |
| Chest wall pain | 1 (7) | 0 | 1 (7) |
| Abdominal pain | 1 (7) | 0 | 3 (21) |
| Hyperglycemia | 1 (7) | 0 | 3 (21) |
| Syncope | 1 (7) | 0 | 1 (7) |
N, number of patients, % of patients.