. 2015 Aug 1;16(1):570. doi: 10.1186/s12864-015-1787-7

Table 1.

Genes selected for functional analysis

Gene	Fold change	FDR	biological function	Brain Enrichment^a
DopR	−0.52	0.028	activation of adenylate cyclase activity	123
CG11155	−0.37	0.108	ion transport	12
sug	−0.82	0	positive and negative regulation of transcription	Eye
sif	−0.58	0.015	regulation of synapse structure and activity, synaptic transmission	25
Thor	−0.36	0.09	negative regulation of translational initiation, antibacterial humoral response	NA
Nf1	−0.51	0.022	locomotor rhythm, cAMP-mediated signalling, regulation of Ras protein signal transduction	17
pho	−0.39	0.075	negative regulation of gene expression	1.6
CalX	−0.38	0.077	Phototransduction	Eye
nrv1	−0.34	0.105	potassium ion transport, sodium ion transport	Eye
modifier of mdg4	−0.42	0.044	regulation of apoptosis, regulation of chromatin assembly or disassembly	2.6
Hr38	0.8	0	phagocytosis, engulfment	24
Fmr1	0.5	0.018	circadian rhythm, brain development, neurotransmitter secretion, synaptic transmission	4.3
CG7589	0.41	0.07	phagocytosis, engulfment	Eye
CG11597	0.6	0.013	protein amino acid dephosophorylation	2.1
CG2051^b	0.44	0.055	histone acetylation; chromatin silencing at telomere	0.6
Nipped-A^b	−0.46	0.034	Signalling, transcriptional co-activator. A key component of both the SAGA and Tip60 (NuA4) chromatin-modifying complexes.	1.9
trithorax^b	−0.41	0.062	histone methylation; histone H3-K4 methylation	4.1
PSc^b	0.48	0.035	chromatin remodelling	1.8
nejire^b	−0.42	0.059	histone acetyltransferase activity, H3-K27 specific, H3-K18 specific
Sirt6^b	0.36	0.082	Predicated histone deacetylation activity, determination of adult life span	0.6
Kr-h1^b	−0.37	0.089	transcription factor activity	2.3
Su(var)3-9^b	0.48	0.024	Histone methyltransferase	2.3

^aEnrichment of expression compared to whole body, data from FlyAtlas.2 [58]

^bGenes associated with chromatin modifications