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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Virology. 2015 May 15;483:117–125. doi: 10.1016/j.virol.2015.02.035

Table 1.

The effect of anti-RSV G protein mAb 131-2G and anti-RSV F protein mAb 143-6C treatments on viral load of BALB/c mice. Viral titer represented as log values.

Groups Day4 pi Day5 pi Day6 pi Day7 pi Day8 pi
r19F 5.84±0.78* 5.29±0.66* 3.14±0.82* ND ND
r19F+143-6C ND ND ND ND ND
r19F+131-2G 2.69±0.09 ND ND ND ND
r19F+nIgG 5.89±0.25 5.31±0.129 3.18±0.58 ND ND
Mock ND ND ND ND ND

BALB/c mice were infected with r19F (1×106 TCID50) on day 0 and administered 300μg of anti-G (131-2G) or anti-F (143-6C) protein mAbs on day 3 pi (n=3 mice/group). Data are means ± SEM.

*

indicates significant difference in viral load for untreated, r19F challenged mice compared with mAb 131-2G and mAb 143-6C treated mice.

Significance (p<0.001) was determined by one-way analysis of variance (ANOVA) and post-hoc Tukey's HSD test. Results are representative of two independent experiments. ND indicates “Not detected”.