Figure 1. Polycistronic lentiviral vectors used in this study.
Diagrams showing lentiviral internal ribosome entry sites (IRES) constructs that were designed to express human APP with Swedish/London FAD mutations (APPSL) along with coexpressed green fluorescent protein (GFP), mCherry, PSEN1 with E9 FAD mutation (PSEN1 E9) mCherry tagged, or both APPSL and PSEN1 E9 FAD mutations together with mCherry. CMV, cytomegalovirus promotor.
