Fig. 6.
Levels of intracellular APP as determined by ELISA (A) and cell viability as determined by MTS assay (B) in MOG-G-UVW cells after incubation with 2B3, 2B12, an anti-N-terminal APP antibody (N, MTS only), or a control irrelevant mouse IgG, all at 10μg/ml for 48 hours. Data are expressed as mean (± SEM) % of control (media only). APP levels were corrected for total cell protein concentration. None of the antibodies tested had any significant effect on levels of APP or cell viability, apart from the anti-N-terminal APP antibody which appeared to stimulate growth. **p<0.01, significantly different from media control using two-tailed Student’s t-tests, n=3.