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. Author manuscript; available in PMC: 2016 Mar 12.
Published in final edited form as: Cell. 2015 Mar 5;160(6):1222–1232. doi: 10.1016/j.cell.2015.02.024

Figure 2. Trpv1 Channels in Agrp Neurons Allow Acute Control of Neuronal Activity.

Figure 2

(A) Main projection from Agrp neurons.

(B) Reporter Trpv1 mice and CFP staining in the arcuate nucleus of Agrp-Trvp1 mice.

(C) Whole-cell recording of an Agrp-Trpv1 neuron and c-fos staining in Agrp-Trpv1-HA reporter mice 60 min after capsaicin injection (10 mg.kg, i.p.).

(D and E) Food intake in (D) female Agrp-Trpv1 and in (E) male mice.

(F) Latency to eat in female Agrp-Trpv1 mice.

(G) Correlation between latency and food intake.

Error bars represent mean ± SEM. Scale bars, 50 μm. See also Figure S1 and Movie S1.