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. 2015 Apr 8;28(6):1292–1300. doi: 10.1021/acs.chemrestox.5b00096

Figure 2.

Figure 2

Cleavage efficiency for dG lesions (A) and rG lesions (B) following the standard chemical cleavage protocols. (A) The dG lesion-containing oligomers were incubated following the standard cleavage recipe that includes fresh, aqueous 1 M piperidine and 0.25 M BME at 90 °C for 30 min. (B) The rG lesion-containing oligomers were incubated following the standard cleavage recipe that includes fresh, aqueous 1 M aniline (pH 4.5) at 60 °C for 20 min in the dark.