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. 2015 Jan 30;6(8):5720–5734. doi: 10.18632/oncotarget.3122

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Copyright: © 2015 Mologni et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A–B) Rotated views of ASP3026 (C atoms shown in orange) docking into ALK-WT. (C–D) Docking of ASP3026 to ALK mutants (C, ALK-D1203N; D, ALK-E1210K) showing a different pose (C atoms in purple). Mutations spots and DFG motif residues are showed in licorice representation (C atoms in cyan and iceblue, respectively).