Table 7.
Correlation between the expression of TLR3 signaling-pathway proteins with those of Ki67, cyclin D1, MMP-2, CD34 and analysis of EPCs in HCC tissues
| Item | N | TLR3 | Spearman | TRIF | Spearman | IRF3 | Spearman | NF-κB | Spearman | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| expression | analysis | expression | analysis | expression | analysis | expression | analysis | ||||||||||||||
| − | + | ++ | γ | P | − | + | ++ | γ | P | − | + | ++ | γ | P | − | + | ++ | γ | P | ||
| Ki-67 | −0.276 | 0.011 | −0.215 | 0.048 | −0.281 | 0.009 | −0.265 | 0.014 | |||||||||||||
| − | 33 | 12 | 4 | 17 | 8 | 9 | 16 | 10 | 12 | 11 | 9 | 12 | 12 | ||||||||
| + | 36 | 12 | 15 | 19 | 12 | 7 | 17 | 19 | 9 | 8 | 12 | 14 | 10 | ||||||||
| ++ | 16 | 11 | 3 | 2 | 6 | 9 | 1 | 11 | 3 | 2 | 10 | 5 | 1 | ||||||||
| CyclinD1 | −0.269 | 0.013 | −0.219 | 0.044 | −0.292 | 0.007 | −0.262 | 0.016 | |||||||||||||
| − | 36 | 11 | 7 | 18 | 10 | 6 | 20 | 11 | 13 | 12 | 12 | 11 | 13 | ||||||||
| + | 28 | 12 | 10 | 6 | 9 | 11 | 8 | 17 | 5 | 6 | 11 | 12 | 5 | ||||||||
| ++ | 21 | 12 | 5 | 4 | 7 | 8 | 6 | 12 | 6 | 3 | 8 | 8 | 5 | ||||||||
| MMP-2 | −0.378 | 0.000 | −0.294 | 0.006 | −0.196 | 0.073 | −0.248 | 0.022 | |||||||||||||
| − | 37 | 10 | 9 | 18 | 8 | 8 | 21 | 15 | 9 | 13 | 11 | 12 | 14 | ||||||||
| + | 25 | 9 | 8 | 8 | 9 | 7 | 9 | 10 | 12 | 3 | 8 | 10 | 7 | ||||||||
| ++ | 23 | 16 | 5 | 2 | 9 | 10 | 4 | 15 | 3 | 5 | 12 | 9 | 2 | ||||||||
| MVD | −0.583 | 0.000 | −0.560 | 0.000 | −0.527 | 0.000 | −0.484 | 0.000 | |||||||||||||
| ≤120 | 23 | 3 | 4 | 16 | 1 | 4 | 18 | 16 | 7 | 2 | 2 | 8 | 13 | ||||||||
| 121–240 | 37 | 11 | 17 | 9 | 9 | 14 | 14 | 15 | 9 | 13 | 12 | 19 | 6 | ||||||||
| >240 | 25 | 21 | 1 | 3 | 16 | 7 | 2 | 22 | 2 | 1 | 17 | 4 | 4 | ||||||||
| EPCs count | −0.544 | 0.000 | −0.458 | 0.000 | −0.277 | 0.010 | −0.345 | 0.001 | |||||||||||||
| ≤5 | 54 | 13 | 18 | 23 | 10 | 14 | 30 | 21 | 17 | 16 | 14 | 23 | 17 | ||||||||
| 6 - 10 | 22 | 14 | 4 | 4 | 8 | 11 | 3 | 10 | 7 | 5 | 10 | 7 | 5 | ||||||||
| >10 | 9 | 8 | 0 | 1 | 8 | 0 | 1 | 9 | 0 | 0 | 7 | 1 | 1 | ||||||||