Figure 2. Comparison of microbiota composition between WKY rats and SHR.
A. The Firmicutes to Bacteroidetes ratio (F/B ratio) was calculated as a biomarker of gut dysbiosis. B. Phylum breakdown of the four most abundant bacterial communities in the WKY (n=5) and SHR (n=6) fecal samples. A decrease of Bacteroidetes along with an increase of Firmicutes resulted in a dysbiosis signature of gut microbiota in SHR rats. A significant reduction of the Actinobacteria phylum correlated with a lower diversity value. Results were compared by student’s t-test; ** p<0.01; ***p<0.001.
