Table 1.
Sample population characteristics
| Obtained from |
Saint Louis University* |
University of Michigan* |
||||
|---|---|---|---|---|---|---|
| Disease diagnosis | HCC† | Cirrhosis † | P | HCC† | Cirrhosis† | P |
| Number | 65 | 32 | N/A | 99 | 81 | |
| Etiology% (HBV/HCV/crypto/alcohol/other)‡ | 14/52/6/20/8 | 0/100/0/0/0 | <0.0001 | 11/51/24/10/4 | 5/48/20/18/9 | 0.1405 |
| Age (mean ± SD) | 58.04 ± 11 | 50 ± 8 | <0.0001 | 58.6 ± 12 | 58 ± 3 | 0.3165 |
| Ethnicity (non-Hispanic White/African-American/Hispanic/Asian) | N/A | N/A | N/A | 86/8/4/2 | 81/11/6/2 | 0.7956 |
| Gender (M:F)% | 71:29 | 84:16 | 0.4079 | 75/25 | 60/40 | 0.053 |
| MELD score (mean ± SD) | 11.8 ± 5 | NA | N/A | 10.3 ± 4 | 9 ± 2 | 0.0026 |
| Child class (A/B/C) or NA%§ | 52:29:9:10 | 88:8:4:0 | <0.0001 | 48/42/10/0 | 40/54/6/0 | 0.1992 |
| Tumor stage (I/II/III/IV)%∥ | 26:48:12:14 | NA | N/A | 21/40/26/13 | NA | N/A |
Abbreviations: MELD, model for end-stage liver disease; N/A, not available.
Samples were provided coded from Saint Louis University Medical School or from the University of Michigan. See text for more details.
Disease diagnosis was determined by MRI or by liver biopsy.
For etiology: crypto, cryptogenic liver disease; alcohol, alcohol-induced liver disease; other, liver disease of unknown origin.
The percentage of patients with each Child-Pugh score is given as a percentage in each group.
Tumor staging was determined using the United Network of Organ Sharing–modified tumor-node-metastasis staging system for HCC. The percentage of patients within each stage is given. Patient’s characteristics were analyzed through the use of χ2 test, Fisher’s exact test, or Welch’s approximate t test as appropriate. All test were two sided, and P < 0.05 was considered significant.