Figure 2. Age-dependent increase in cardiac size in sFRP-1 KO mice.
(A) Representative picture from whole heart of WT and sFRP-1 KO mice at 12 months of age showing increase in heart size. (B) Heart weight/body weight ratio (mg/g) of the sFRP-1 KO mice at 6 months and 12 months of age (n=5) compared to their WT littermates. Significant differences were denoted by *P < 0.05 < or **P < 0.01, or ***P < 0.001. > vs control littermate hearts. All values were expressed as mean ± SEM.
