Figure 4.

Characterization of differentially expressed proteins in human pancreatic islets. (A) Bar graph of the fold changes for differentially expressed proteins. Vertical line over 0 indicates value for condition control (+serum). Red bars absence of serum (-serum). Blue bars absence of serum supplemented with 10μM of DETA/NO (-serum + DETA/NO). Statistical significance Student´s test p-value < 0.005 (B) Top biological functions displayed by significance score (-log(p-value)). p-value < 0.005. (C) Pye chart for sub-cellular localization distributed by percentage of proteins with respect to the total of correctly identified proteins. (D) Pie chart for protein functions distributed by percentage of proteins with respect to the total of correctly identified proteins. DRR: DNA replication recombination repair.