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. 2015 Mar 16;33(12):1389–1396. doi: 10.1200/JCO.2014.58.0209

Table A6.

HRs for MSS According to Quintile of CRP Plasma Level in Patients With Any-Stage Disease

Quintile of Plasma Level Median (mg/L) Quintile Value (mg/L) Univariable Analysis
Multivariable Analysis*
HR 95% CI Trend P HR 95% CI Trend P
1 0.33 < 0.55 1.00 < .001 1.00 < .001
2 0.86 0.55-1.18 2.68 1.51 to 4.75 1.93 1.08 to 3.44
3 1.69 1.18-2.35 2.13 1.18 to 3.86 1.55 0.85 to 2.82
4 3.46 2.35-5.38 2.23 1.24 to 4.03 1.64 0.90 to 2.98
5 10.57 ≥ 5.38 5.31 3.09 to 9.13 3.44 1.99 to 5.94

Abbreviations: CRP, C-reactive protein; HR, hazard ratio; MSS, melanoma-specific survival.

*

Adjusted for age, sex, stage at blood draw, storage time, and data set.