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. Author manuscript; available in PMC: 2015 Apr 6.
Published in final edited form as: Cancer Res. 2006 Jun 15;66(12):6063–6071. doi: 10.1158/0008-5472.CAN-06-0054

Figure 6.

Figure 6

Hypothetical model depicting mammary stem cell self-renewal pathways in normal and cancer stem cells. Arrows, activation of the pathways by ligands; cyclopamine is an inhibitor of hedgehog signaling.