. 2015 Jan 16;2(3):255–263. doi: 10.1016/j.ebiom.2015.01.008

Table 2.

BECN1 and BRCA1 expression association with clinical features (METABRIC cohort).

	BECN1 expression				BRCA1 expression
mRNA expression		Odds ratio (95% confidence interval)	P value	mRNA expression		Odds ratio (95% confidence interval)	P value
High	Low	High	Low
PAM50 subtypes
Luminal A/B	804	409	Reference		656	557	Reference
HER2-enriched	63	177	5.5 [4.0, 7.7]	1.4E− 30	136	104	0.9 [0.7, 1.2]	0.48
Basal-like	54	277	10.0 [7.3, 14.1]	1.4E− 61	168	163	1.1 [0.9, 1.5]	0.29
TP53 mutation
Wild type	423	298	Reference		345	376	Reference	0.52
Mutant	32	67	3.0 [1.9, 4.8]	8.9E− 07	51	48	0.9 [0.6, 1.3]
Tumor grade
I	111	59	Reference		53	117	Reference
II	462	313	1.3 [0.9, 1.8]	0.194	371	404	0.5 [0.3, 0.7]	8.3E− 05
III	379	578	2.9 [2.0, 4.1]	5.8E− 10	526	431	0.4 [0.3, 0.5]	1.1E− 08