Table 2.
Adjusted analysis of risk factors associated with overall survival (OS)
| At risk, n | Deaths, n | Median OS (95% CIa) | HR (95% CI) | P-value | |
|---|---|---|---|---|---|
| Unvaccinated patientsb | 0.006 | ||||
| Female | 11 | 10 | 14.7 (8.4–25.1) | 1.00 | |
| Male | 17 | 13 | 21.7 (12.1–83.9) | 0.25 (0.09–0.67) | |
| Vaccinated patientsb | 0.500 | ||||
| Female | 17 | 13 | 25.0 (13.8–41.4) | 1.00 | |
| Male | 21 | 20 | 23.6 (17.8–31.2) | 1.28 (0.62–2.64) | |
| Margin status | 0.027 | ||||
| Negative | 35 | 28 | 26.3 (16.1–40.0) | 1.00 | |
| Positive | 31 | 28 | 18.1 (14.0–25.0) | 1.97 (1.08–3.58) | |
| Stromal density | 0.004 | ||||
| <0.8 | 26 | 24 | 14.4 (10.6–23.7) | 1.00 | |
| ≥0.8 | 40 | 32 | 25.1 (20.9–34.3) | 0.44 (0.25–0.77) |
a
Confidence intervals for median OS are computed based upon the log hazard.
b
Test of interaction between gender and treatment was statistically significant (P = 0.008).
95% CI, 95% confidence interval; HR, hazard ratio.