Figure 2.
Intra-colonic administration of propionate increases jugular and portal vein plasma gut hormone concentrations in male Wistar rats. Blood samples were collected over a 60-min period, via a jugular vein cannula (a, c), and at t=15 min from the portal vein (b, d), following an intra-colonic injection (2.5 ml) of 180 mmol l−1 propionate or saline (matched for pH and sodium content) in isoflurane-anaesthetised rats. Data represent means±s.e.m. (n=10–14 per group). Significance was determined using two-way ANOVA (a, c) or unpaired t-test (b, d) (*P<0.05).