FIG. 1.
Hypoglycemia outcomes from six treatment modalities plotted (A and C) against sensor mean absolute relative difference (MARD) and (B and D) against the frequency of sensor errors exceeding 20%: (A and B) percentage of blood glucose values below 50 mg/dL and (C and D) frequency of blood glucose readings ≤39 mg/dL within a 12-h time period. POC, point-of-care treatment equivalent to direct dosing using a sensor value; Threshold, addition of threshold alarms to prevent hypoglycemia; Predictive, addition of predictive alarms to prevent hypoglycemia. POC+Arrow, Threshold+Arrow, and Predictive+Arrow are settings that use additional insulin reduction based on downward trend arrows displayed by the sensor.