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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Nature. 2014 Dec 15;517(7532):50–55. doi: 10.1038/nature14063

Extended Data 4. Sequence alignment of RyR orthologues.

Extended Data 4

Secondary structural elements are indicated above the sequence alignment and domains are colored the same as the structures shown in the main text figures. The numbering of the secondary elements refers to their sequential positions within the corresponding domains. Invariant amino acids are shaded light grey. The GI codes for the sequences from top to bottom: rabbit RyR1 (156119408), human RyR1 (113204615), human RyR2 (308153558), and human RyR3 (325511382).