Table 2.
Hazard Ratios per Standard Deviation for Log-Transformed Resistin
| Hazard Ratio* per SD log [resistin] | ||||||
|---|---|---|---|---|---|---|
| Events (N, %) | Unadjusted | Model 1 | Model 2 | Model 3 | Model 4 | |
| AF | 52, 2.72% | 1.1 (0.9–1.5) |
1.0 (0.7–1.3) |
0.9 (0.7–1.2) |
0.9 (0.7–1.3) |
0.9 (0.7–1.2) |
| HF | 58, 3.12% |
1.9 (1.5–2.5) |
1.7 (1.3–2.2) |
1.5 (1.1–2.1) |
1.5 (1.1–2.0) |
1.4 (1.0–2.0) |
| CVD (hard) | 110, 5.76% |
1.5 (1.3–1.8) |
1.4 (1.1–1.7) |
1.3 (1.1–1.6) |
1.3 (1.1–1.6) |
1.3 (1.1–1.7) |
| CVD (all) | 152, 7.95% |
1.5 (1.2–1.7) |
1.4 (1.2–1.6) |
1.3 (1.1–1.5) |
1.3 (1.1–1.5) |
1.3 (1.1–1.6) |
| CHD | 106, 5.55% |
1.5 (1.2–1.8) |
1.4 (1.2–1.8) |
1.3 (1.1–1.7) |
1.3 (1.0–1.6) |
1.3 (1.0–1.6) |
| Death | 147, 7.69% |
1.3 (1.1–1.5) |
1.1 (0.9–1.3) |
1.0 (0.9–1.2) |
1.0 (0.9–1.3) |
1.0 (0.8–1.2) |
Model 1: Age, Sex, Race. Model 2: Model 1 + hypertension, hypertension medications, diabetes mellitus, cigarette smoking, total cholesterol, HDL cholesterol, lipid therapy. Model 3: Model 2 + BMI, HOMA-IR, log(hs-CRP). Model 4: Model 3 + leptin, adiponectin
Abbreviations: AF, Atrial Fibrillation; HF, Congestive Heart Failure; CVD, Cardiovascular Disease; CHD, Coronary Heart Disease
*
Hazard Ratios are expressed per standard deviation of log-transformed resistin