Figure 2. Distribution of microglial cells and BMDCs in the injured spinal cord in CX3CR1GFP/+ mice (A and B) or CX3CR1GFP/+ mice reconstituted with RFP+ BM cells (C).
All microglial cells were CX3CR1high. Dashed lines mark the lesion site. A. Distribution of microglial cells (CX3CR1high) in spinal cord sections from CX3CR1GFP/+ mice at indicated time after SCI. B. Distribution of CX3CR1high and CX3CR1low cells in spinal cord from CX3CR1GFP/+ mice at 2 weeks after injury. Both populations were positive for IBA-1 staining (red). C. Distribution of microglial cells and BMDCs in the lesion site in CX3CR1GFP/+ mice reconstituted with RFP+ BM cells at 2 weeks after injury. Sections were labeled with F4/80 antibody (purple). Bars: (A) 400 μm; (B) 40 μm; (C) 30 μm.
