Table 3.
Univariable analysis: restriction spectrum imaging (RSI) z-score and apparent diffusion coefficient (ADC) are independently investigated comparing individual regions of interest to their corresponding primary Gleason pattern.
| Sample size method | Means | Statistical test | p value | ||
|---|---|---|---|---|---|
| Detection of increasingly aggressive cancera | Mean (standard error) | F-test | |||
| 64 | Restricted spectrum imaging (RSI) z-score | 97.7 | <0.001 | ||
| Benign | 0.65 (0.12) | ||||
| Primary Gleason 3 | 2.4 (0.61) | ||||
| Primary Gleason 4 | 2.9 (0.51) | ||||
| 64 | Apparent diffusion coefficient (ADC) | 13.9 | <0.001 | ||
| Benign | 1680 (428) | ||||
| Primary Gleason 3 | 1237 (425) | ||||
| Primary Gleason 4 | 967 (221) | ||||
| Prostate cancer aggressivenessb | Mean difference | t-test | |||
| 36 | Restricted spectrum imaging (RSI) z-score | 34 | 0.5 | 2.22 | 0.033 |
| 36 | Apparent diffusion coefficient (ADC) | 34 | 269 | 1.81 | 0.079 |
The top half of the table uses ANVOA analysis to determine differences in detection comparing benign vs. primary Gleason 3 vs. Primary Gleason 4 prostate cancer. The bottom half of the table only compares Gleason 3 vs. 4 cancers with a t-test.
aBenign vs. Gleason 3 vs. Gleason 4.
bGleason 3 vs. Gleason 4.