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. 2015 Feb 5;6:6046. doi: 10.1038/ncomms7046

Table 1. Association statistics for the 36 previously reported psoriasis susceptibility loci.

SNP Chr. Position (bp) Notable genes Risk/non-risk allele RAF (case) RAF (control) P-value OR Tsoi SNP r2 Tsoi SNP
rs33980500 6 111,913,262 TRAF3IP2 T/C 0.11 0.07 2.65E−16 1.6 rs33980500 1
rs4921482 5 158,764,478 IL12B | ADRA1B T/C 0.74 0.67 1.47E−15 1.4 rs4379175 0.85*
rs12044149 1 67,600,686 IL23R T/G 0.32 0.25 2.25E−15 1.4 rs9988642 0.14
rs2020854 12 56,743,367 STAT2 T/C 0.96 0.93 7.73E−10 1.7 rs2066819 0.99
rs34725611 19 10,477,067 TYK2 A/G 0.76 0.71 2.99E−09 1.3 rs34536443 0.09
rs76956521 5 150,464,641 TNIP1 | ANXA6 C/A 0.08 0.05 4.98E−09 1.5 rs2233278 1
rs4795067 17 26,106,675 NOS2A G/A 0.39 0.34 1.94E−07 1.2 rs28998802 0.06
rs984971 2 163,224,521 IFIH1 T/G 0.68 0.64 3.62E−06 1.2 rs17716942 0.3
rs7523412 1 25,294,264 RUNX3 | SYF2 A/G 0.54 0.5 5.42E−06 1.2 rs7536201 0.99
rs848 5 131,996,500 IL13 C/A 0.85 0.82 1.05E−05 1.2 rs1295685 0.96
rs7552167 1 24,518,643 IL28RA | GRHL3 G/A 0.89 0.86 1.53E−05 1.3 rs7552167 1
rs6063454 20 48,590,791 ZNF313 | SNAI1 G/T 0.63 0.59 2.90E−05 1.2 rs1056198 0.9
rs1306395 2 61,076,272 PAPOLG | REL T/C 0.61 0.57 2.99E−05 1.2 rs62149416 0.77
rs1133071 9 32,455,674 DDX58 C/T 0.34 0.3 3.36E−05 1.2 rs11795343 0.18
rs892085 19 10,818,092 ILF3 T/C 0.59 0.55 4.02E−05 1.2 rs892085 1
rs2298428 22 21,982,892 LOC150223 T/C 0.2 0.18 4.38E−05 1.2 rs4821124 0.96
rs6713082 2 62,516,544 B3GNT2 | TMEM17 A/C 0.27 0.24 4.59E−05 1.2 rs10865331 0.29
rs8016947 14 35,832,666 PSMA6 | LOC122589 G/T 0.6 0.56 9.65E−05 1.2 rs8016947 1
rs4796659 17 40,590,029 PTRF | ATP6V0A1 G/T 0.93 0.91 0.000132 1.3 rs963986 0.01
rs62376445 5 96,196,721 ERAP1 | ERAP2 C/A 0.96 0.94 0.000174 1.4 rs27432 0.02
rs610604 6 138,199,417 TNFAIP3 G/T 0.35 0.32 0.000325 1.1 rs582757 0.78
rs7761186 6 512,951 EXOC2 | LOC727827 T/C 0.99 0.98 0.000709 1.8 rs9504361 0.01
rs645078 11 64,135,298 RPS6KA4 A/C 0.64 0.61 0.00086 1.1 rs645078 1
rs11121129 1 826,8095 ERRFI1 | SLC45A1 A/G 0.33 0.3 0.000934 1.1 rs11121129 1
rs4936059 11 128,502,496 ETS1 | FLI1 G/A 0.35 0.32 0.001475 1.1 rs3802826 0
rs12928822 16 11,403,893 PRM1 | C16orf75 C/T 0.84 0.81 0.001593 1.2 rs367569 0.56
rs6693105 1 152,590,663 LCE3B | LCE3A C/T 0.68 0.65 0.002892 1.1 rs6677595 1
rs7197717 16 31,083,075 ZNF668 C/A 0.41 0.38 0.003544 1.1 rs12445568 0.92
rs4561177 11 109,962,432 LOC260340 | ZC3H12C A/G 0.6 0.57 0.003782 1.1 rs4561177 1
rs73112675 7 37,379,030 ELMO1 G/A 0.2 0.17 0.004116 1.1 rs2700987 0.18
rs602422 18 51,805,130 POLI C/T 0.31 0.29 0.004767 1.1 rs545979 1
rs1972346 10 81,067,480 ZMIZ1 C/G 0.61 0.59 0.008258 1.1 rs1250546 0.4
rs11652075 17 78,178,893 CARD14 C/T 0.51 0.49 0.01423 1.1 rs11652075 1
rs1973919 6 159,440,727 RSPH3 | TAGAP C/T 0.33 0.31 0.01812 1.1 rs2451258 0.22
rs12236285 9 110,855,243 LOC392382 A/G 0.08 0.07 0.03838 1.2 rs10979182 0.03

bp, base pair; Chr, chromosome; OR, odds ratio; RAF, risk allele frequency.

*Tsoi secondary effect.