Table 1.
Baseline patient characteristics
| Untreated PHPT (n = 43) | Treated PHPT (n = 25) | Controls (n = 47) | Reference ranges | |
|---|---|---|---|---|
| Age (years) | 62.9 ± 13.8 | 63.6 ± 13.6 | 61.1 ± 14.9 | |
| Height (m) | 1.63 ± 0.11 | 1.64 ± 0.09 | 1.66 ± 0.10 | |
| Weight (kg) | 78.9 ± 18.0 | 75.3 ± 16.7 | 74.4 ± 13.5 | |
| Female : Male | 31:12 | 17:8 | 31:16 | |
| Caucasian : Hispanic : African American | 41:1:1 | 24:1:0 | 47:0 | |
| Melbourne : New York patients | 31:12 | 15:10 | 47:0 | |
| Time since diagnosis (years) | 1.9 ± 2.0 | |||
| Time since surgery (years) | 5.3 ± 5.3 | |||
| Corrected serum calcium (mmol/L) | 2.66 ± 0.16ab | 2.41 ± 0.20a | 2.42 ± 0.11b | 2.10 – 2.60 |
| Serum phosphate (mmol/L) | 1.02 ± 0.21 | 1.10 ± 0.16 | 1.24 ± 0.20 | 0.60 – 1.40 |
| Serum PTH (pmol/L) | 13.0 ± 5.7ab | 6.4 ± 4.3a | 4.1 ± 0.9b | 1.6 – 6.9 |
| Serum 25(OH)D (nmol/L) | 58.9 ± 13.8 | 55.4 ± 18.1 | 54.5 ± 23.3 | >75c |
| % supplementated with cholecalciferol | 48 | 47 | 45 | |
| % supplementated with calcium | 0 | 26 | 20 |
Values expressed as mean ± SD
a
Untreated PHPT vs. Treated PHPT p <0.05
b
Untreated PHPT vs. Control p <0.05
c
Represents the desirable level of 25(OH) vitamin D at our institution