Table 1.
Patient tumour characteristics
| No | Age | Origin | Stage | Histology | Patient genomics | PDX | Days | Tissue status |
|---|---|---|---|---|---|---|---|---|
| 1 | 1y4m | primary (AG) | IV | un NB | MYCN amp, 1p- | yes | 70 | Cryopreserved |
| 2 | 2y2m | cerebral met | IV | un NB | MYCN amp, 1p-,+17q | yes | 102 | Cryopreserved |
| 3 | 2y9m | primary (AG) | III | pd NB | MYCN amp, 1p-, +17q | yes | 59 | Fresh |
| 4 | 4y9m | primary (AG) | IV | pd NB | MYCN gain, 1p-, 11q-,+17q | no | NA | Cryopreserved |
| 5 | 2y4m | primary (AG) | IV | pd NB | 1p-,+17q | no | NA | Cryopreserved |
| 6 | 12y | primary | IIb | pd NB | +17q | no | NA | Cryopreserved |
AG = adrenal gland, un NB = undifferentiated neuroblastoma, pd NB = poorly differentiated neuroblastoma. Numbers of days refer to the time period from implantation until PDXs were analysed.