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Schematic diagram of mutations observed in ERBB2. Mutation frequency at each residue is depicted by vertical red bars. All exon 20 insertions (ex20ins) are graphed in red; however, only the most frequent site is labeled (A775_G776insYVMA). For a complete list of exon 20 alterations and the diseases in which they occur, see supplemental online Table 3.
Abbreviation: CRC, colorectal cancer.
