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. Author manuscript; available in PMC: 2014 Dec 31.
Published in final edited form as: Mol Cell. 2011 Sep 16;43(6):950–961. doi: 10.1016/j.molcel.2011.06.031

Figure 7. Model.

Figure 7

Negative feedback regulatory loops buffer NMD from genetic and environmental perturbations, allowing NMD to maintain its functions in regulating gene expression and RNA surveillance.