Table 1.
Baseline Characteristics by ST2 Quartile
| Quartiles of Baseline ST2, pg/mL | |||||
|---|---|---|---|---|---|
| Baseline Characteristics | 0 (n=367) | 3–79 (n=250) | 80–325 (n=312) | >325 (n=310) | P for Trend |
| Age, y | 57.1±10.2 | 58.0±10.7 | 58.8±9.9 | 58.3±10.4 | 0.08 |
| Female, n (%) | 74 (20.2) | 46 (18.4) | 63 (20.2) | 71 (22.9) | 0.36 |
| BMI, kg/m2 | 27.6±4.0 | 27.7±4.2 | 27.5±4.2 | 27.7±5.3 | 0.98 |
| Hypertension, n (%) | 131 (35.9) | 93 (37.5) | 133 (43.3) | 126 (40.9) | 0.08 |
| Current smoker, n (%) | 185 (50.4) | 112 (44.8) | 145 (46.9) | 143 (46.1) | 0.33 |
| Diabetes mellitus, n (%) | 36 (9.9) | 49 (19.6) | 61 (19.7) | 67 (22.0) | <0.0001 |
| Hyperlipidemia, n (%) | 127 (39.3) | 99 (45.6) | 116 (41.4) | 103 (38.4) | 0.72 |
| Prior MI, n (%) | 31 (8.5) | 24 (9.6) | 28 (9.0) | 21 (6.8) | 0.46 |
| Prior CHF, n (%) | 6 (1.7) | 4 (1.6) | 2 (0.6) | 3 (1.0) | 0.27 |
| Creatinine clearance, mL/min | 93.5±30.1 | 93.5±32.2 | 89.1±30.1 | 87.7±33.0 | 0.008 |
| Index presentation | |||||
| Time from symptom onset to lytic, h | 2.7±1.8 | 2.8±1.8 | 3.3±2.1 | 3.5±2.7 | <0.0001 |
| Anterior MI, n (%) | 125 (34.1) | 95 (38.0) | 113 (36.2) | 133 (42.9) | 0.04 |
| Killip class II–IV, n (%) | 23 (6.3) | 10 (4.0) | 27 (8.7) | 27 (8.7) | 0.08 |
| Fibrin-specific lytic, n (%) | 334 (91.0) | 216 (86.4) | 263 (84.3) | 260 (83.9) | 0.004 |
| Peak CK, IU/L | 1694±1535 | 1895±2058 | 1986±1754 | 2293±2503 | 0.0002 |
BMI indicates body mass index. Data are presented as mean±SD for continuous variables and number (%) for dichotomous variables.