Figure 8. Neutralization Activity Against a Panel of HIV-1 isolates is elicited in rabbits co-immunized with Env(MPER)-E2 and either SF162 gp160full-length, ΔV3, ΔV2, or ΔV123 DNA.
(A) Neutralization titers against the autologous SF162, Bal.26, SS1196.1 ZM109F.PB4, YU2, JRFL, and JRCSF pseudoviruses were determined using the TZM-bl assay. Values stated are the IC50 values for individual rabbits in each of the four groups at weeks 6 (A), 14 (B), and 28 (C). Darker colors represent an increase in NAb titer.
