Figure 3.
Alignment of human Pol α–DNA/RNA ternary complexes containing aphidicolin or dCTP. (A) The overall view of aligned ternary complexes. Proteins are represented as cartoon, all other molecules as sticks. For the complex with aphidicolin, the protein is colored pale-green, aphidicolin—yellow and DNA/RNA carbons—gray. For the complex containing dCTP, the protein is colored salmon, DNA/RNA—cyan and dCTP—marine. (B) Close-up view of aligned aphidicolin, dCTP and surrounding DNA/RNA bases. All atoms in aphidicolin complex are shown as sticks, and in dCTP complex as lines. For the ternary complexes containing aphidicolin or dCTP, the carbon atoms of DNA/RNA are colored gray or cyan, respectively.