Figure 6. EF Stimulation of Networks Exhibiting Cortical Oscillations with Variable UP and DOWN state duration.
(A) Spectrum of the 10 s optogenetic stimulation waveform (cyan). EF stimulation frequencies are indicated in black. (B) Left: Spectra of the response to 1 Hz square-wave optogenetic stimulation (gray) and response to temporally variant optogenetic stimulation (blue). Right: Response optogenetic stimulation, normalized by the oscillation amplitude at 1 Hz. (C) Spectra of the enhancement of oscillations by EF stimulation for 0.8 (green), 1.0 (yellow), 1.2 (red), 2.0 (blue) Hz stimulation. (D) Left: Frequency preference for oscillations at the frequency of the EF stimulation. Right: Frequency preference for 1 Hz oscillations. Error bars indicate 5 to 95% confidence interval. * p < 0.05.
