TABLE 2.
Residues in distal pocket having a higher contribution to substrate binding in AcrB than the corresponding residues in AdeB and AdeJa
| Residue in AcrB | Residue in: |
|
|---|---|---|
| AdeB | AdeJ | |
| F136 | F | F |
| V139 | L | V |
| Q176 | Q | Q |
| F178 | F | F |
| G179 | G | G |
| S180 | A | G |
| I277 | F | F |
| I278 | A | D |
| Y327 | Y | Y |
| F610 | T | F |
| V612 | I | V |
| F615 | W | F |
| R620 | A | V |
| F628 | F | F |
Data for AcrB are from reference 16.