Table 2.
Maximum affect of DR on lifespan across mutant strains
| Genotype | Average max % increase lifespan vs. AL | SEM | Food conc. (A600) | # Indep. expr. | P-value 2-way ANOVA vs. Ctrl. |
|---|---|---|---|---|---|
| N2 | 85 | < 0.0 | 0.01 | 21 | NA |
| daf-16 | 39 | 0.2 | 0.00 | 3 | < 0.0001 |
| skn-1 | 21 | 1.3 | 0.50 | 6 | < 0.0001 |
| aak-2 | 30 | 1.1 | 0.00 | 2 | < 0.0001 |
| sir-2.1 | 47 | 1.3 | 0.00 | 4 | < 0.0001 |
| sir-2.1;sir-2.2;sir-2.4 | 36 | 2.7 | 0.00 | 2 | 0.0001 |
| sir-2.1;sir-2.3;sir-2.4 | 62 | 1.6 | 0.00 | 2 | < 0.0001 |
| pnc-1 | 32 | 0.9 | 0.50 | 10 | < 0.0001 |
| smg-1 | 45 | 2.5 | 0.00 | 4 | NA |
| pha-4;smg-1 | 10 | 1.0 | 0.00 | 4 | 0.0004 |
This table presents the DR food concentration at which each strain experiences its maximal lifespan extension, in comparison to its lifespan on AL food, as well as what the percent increase in lifespan is. The wild-type N2 is the control for all strains except for pha-4;smg-1, whose genetic control is smg-1.
The percent change experienced by the control strains is in bold.