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Electrophysiology of Caco-2BBe Myo5b kd cells. A: transepithelial electrical resistance (TER) in Caco-2BBe cells (scrambled or Myo5b kd) grown for 15 days, supplemented (or not) with 5 μM BX-912 PDK1 inhibitor overnight. B: short-circuit current in Ringer solution (black) or the same cells in a modified Ringer with Cl− replaced by gluconate (gray bar). BX-912 was used as in A. Data are presented as averages ± SD (n = 3).
