Figure 3. Reclassification of 4 Year Predictive Probabilities of Pump Failure with Addition of Novel Biomarkers.
Graphic representation of reclassification across low and high risk of pump failure and change in predicted probabilities with addition of galectin-3 and ST2 to Clinical model + NT-proBNP in entire cohort (top panel), cases (middle panel), and controls (bottom panel). Overlapping shading in risk categories represents the number of patients reclassified with addition of galectin-3 (left column), ST2 (middle column), and ST2+galectin-3 (right column). For example, among all patients (top panel), the addition of galectin-3 (left most column) moved 23 low risk patients into the high risk category, and 25 high risk patients to the low risk category.
