Fig. 6.

Vascular production of nitric oxide (NO) following methacholine challenge in male and female mice following 8 wk of UCMS. Data are presented for vessels under control (untreated) conditions, following treatment of vessels from UCMS animals with TEMPOL and following treatment of vessels from UCMS animals with l-NAME. Control males n = 9; control females n = 7; UCMS males n = 8; UCMS females n = 8. *P < 0.05 vs. responses in control vessels from mice of that sex; †P < 0.05 vs. responses in untreated vessels of UCMS mice of that sex; ‡P < 0.05 vs. responses in UCMS + TEMPOL-treated mice of that sex.