Figure 1.
Representative images of nerves with H&E and S-100 immunolabeling staining. The macrophages were studied using immunolabeling with the macrophage marker CD68 and the M2-type macrophage marker CD163. (A), (E) H&E staining of the nerves. (B), (F) S-100 immunohistochemical staining of the nerves. (C), (G) CD68 immunohistochemical staining of the macrophages. (D), (H) CD163 immunohistochemical staining of the macrophages. (A) to (D), Tumor tissue samples with intra-PDA lesions. (E) to (H), Benign pancreatic tissues. (a) to (h) Magnified images of (A) to (H), respectively. PDA, pancreatic ductal adenocarcinoma. N, nerve's bundle. Positive staining is shown in brown.