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. Author manuscript; available in PMC: 2015 Jan 17.
Published in final edited form as: Nature. 2014 Jun 1;511(7509):348–352. doi: 10.1038/nature13294

Extended Data Figure 8. The effects of LTD and LTP are rapid and long-lasting.

Extended Data Figure 8

Animals (n=5) were tested for CR one day following pairing of optical CS with shock (a). Within one hour of testing animals received optical LTD protocol and were tested for CR 20 minutes (b) and three days (c) later. Following day three testing animals received optical LTP protocol and were tested for CR 20 minutes (d) and three days (e) later. f, Graph of normalized lever presses for first minute of optical CS following indicated protocols.