Figure 5.
viability and differentiation of mc3t3 cells encapsulated in 10% gelma hydrogels comparing constructs with fabricated microchannels versus blocks without microchannels. live and dead images of gelma hydrogel blocks (a and b) and hydrogels with fabricated microchannels (c and d) at days 1 and 7. e) hydrogel blocks had significantly lower viability at day 1 (*p<0.05) and day 7 (***p<0.001). f) alp specific activity assay showed significantly higher alp activity levels in cell-laden constructs with microchannels versus cell-laden hydrogel blocks on day 14 (****p<0.0001).(scale bar 700 μm)