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LETM1 is dispensable for IMCU. Mitoplast Ca2+ current (IMCU) from HeLa cells was recorded before and after application of 5 mM Ca2+ to the bath medium. Currents were measured during a voltage ramp as indicated. Traces are a representative single recording of IMCU from neg shRNA (black; A) and LETM1 KD (red; B). C) IMCU densities (pA/pF) for neg shRNA (black) and LETM1 KD (red). Data are expressed as means ± sem (n=4). ns, not significant.
