Table 2.
Summary of results from multiple regressions investigating relation between age, ROI size, and tract measures controlling for motion in the entire sample (N = 35)
| RILF |
LILF |
RIFOF |
LIFOF |
|||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| F | P | r2 change | PAge | PROI size | F | P | r2 change | PAge | PROI size | F | P | r2 change | PAge | PROI size | F | P | r2 change | PAge | PROI size | |
| Non-normalized volume | ||||||||||||||||||||
| FFA | 8.6 | <0.001 | 0.42 | <0.008 | <0.008 | 6.4 | <0.001 | 0.41 | <0.001 | ns | 1.3 | ns | 0.5 | ns | ||||||
| OFA | 5.0 | <0.001 | 0.28 | <0.005 | ns | 6.3 | <0.001 | 0.41 | <0.001 | ns | 1.3 | ns | 0.5 | ns | 0.5 | ns | 0.5 | |||
| PPA | 4.9 | <0.005 | 0.28 | <0.005 | ns | 8.3 | <0.001 | 0.48 | <0.001 | <0.05 | 1.1 | ns | 0.4 | ns | ||||||
| Normalized volume | ||||||||||||||||||||
| FFA | 6.6 | <0.001 | 0.39 | <0.025 | <0.01 | 4.7 | <0.005 | 0.34 | <0.005 | ns | 1.2 | ns | 0.4 | ns | ||||||
| OFA | 4.2 | <0.01 | 0.28 | <0.01 | ns | 4.3 | <0.008 | 0.32 | <0.005 | ns | 1.2 | ns | 0.4 | ns | ||||||
| PPA | 3.7 | <0.025 | 0.25 | <0.005 | ns | 5.5 | <0.005 | 0.38 | <0.005 | ns | 1.0 | ns | 0.2 | ns | ||||||
| Microstructural indices | ||||||||||||||||||||
| FFA | ||||||||||||||||||||
| FA | 1.8 | ns | 0.9 | ns | 2.3 | ns | 1.3 | ns | ||||||||||||
| MD | 6.2 | <0.001 | 0.28 | <0.025 | ns | 3.1 | <0.05 | 0.26 | <0.01 | ns | 3.4 | <0.025 | 0.12 | <0.05 | ns | 3.1 | <0.05 | .26 | <0.01 | ns |
| RD | 7.4 | <0.001 | 0.26 | <0.025 | ns | 3.9 | <0.025 | 0.25 | <0.01 | ns | 3.7 | <0.025 | 0.16 | <0.05 | ns | 3.9 | <0.025 | .25 | <0.01 | ns |
| OFA | ||||||||||||||||||||
| FA | 1.6 | ns | 0.8 | ns | 2.2 | ns | 1.4 | ns | ||||||||||||
| MD | 4.6 | <0.005 | 0.21 | <0.008 | ns | 3.1 | <0.05 | 0.26 | <0.005 | ns | 3.4 | <0.025 | 0.11 | ns | ns | 1.1 | ns | |||
| RD | 6.1 | <0.001 | 0.21 | <0.008 | ns | 4.1 | <0.01 | 0.25 | <0.005 | ns | 3.8 | <0.025 | 0.17 | <0.05 | ns | 2.0 | ns | |||
| PPA | ||||||||||||||||||||
| FA | 2.1 | ns | 1.0 | ns | 2.3 | ns | 0.8 | ns | ||||||||||||
| MD | 4.6 | <0.005 | 0.21 | <0.008 | ns | 3.0 | <0.05 | 0.25 | <0.005 | ns | 3.4 | <0.025 | 0.11 | ns | ns | 1.2 | ns | |||
| RD | 6.4 | <0.001 | 0.23 | <0.01 | ns | 3.8 | <0.025 | 0.24 | <0.008 | ns | 3.8 | <0.025 | 0.17 | <0.05 | ns | 1.2 | ns | |||
Note: Full model for each regression included 2 motion factors, age, and ROI size with the following degrees of freedom (4, 29). r2 change represents the additional variance accounted for in the model by the factors of interest (age, ROI size) after accounting for motion in both the y- and z-directions. In addition, regressions were all run within the hemisphere (e.g., the size of right FG ROI predicting the volume of right ILF). Bold P-values represent those that survived the Bonferroni correction of P < 0.008.
ILF: inferior longitudinal fasciculus; IFOF: inferior fronto-occipital fasciculus; FA: fractional anisotropy; FFA: fusiform face areas; OFA: occipital face area; PPA: parahippocampal place area; MD: mean diffusivity; RD: radial diffusivity.