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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Nature. 2014 Mar 30;509(7498):105–109. doi: 10.1038/nature13148

Figure 1. Quantitative proteomics for identification of autophagosome-associated proteins.

Figure 1

(a) Autophagosome enrichment workflow. (b) Log2(H:L) plot for autophagosome proteins from PANC1 cells (Ex. 3, Table S3) and scheme for identification of candidate autophagosome proteins. (c) Autophagosome candidate overlap from biologic replicate experiments for PANC1 and MCF7 cells, as well as overlap between PANC1 and MCF7 datasets. (d) Pearson correlation plot for overlapping candidates from PANC1 experiments (86 proteins, comparing Ex. 2 vs. Ex. 3). (e) Log2(H:L) heat map of Class 1A candidates from PANC1 and MCF7 cells.